Details

Autor(en) / Beteiligte

• Van Nostrand, D
• Abreu, S H
• Callaghan, J J
• Atkins, F B
• Stoops, H C
• Savory, C G

Titel

In-111-labeled white blood cell uptake in noninfected closed fracture in humans: prospective study

Ist Teil von

• Radiology, 1988-05, Vol.167 (2), p.495

Ort / Verlag

United States

Erscheinungsjahr

1988

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Since indium-111 white blood cell (In-111 WBC) scintigraphy is often used to evaluate for osteomyelitis in bone fractures, it is important to know if noninfected fractures have In-111 WBC uptake. Twenty-seven noninfected closed fracture sites in 19 patients were prospectively evaluated with technetium-99m methylene diphosphonate bone scintigraphy and In-111 WBC scintigraphy. In-111 WBC uptake was present in 41% of the 27 sites. In the 11 positive sites, the In-111 WBC uptake was 1+ (definite but minimal) in 55%, 2+ (moderate) in 36%, and 3+ (marked) in 9%. The visual intensity of the radioactive uptake on In-111 WBC scintigrams relative to that on bone scintigrams was less in 82%, equal in 9%, and greater in 9%. The visual size of the area of uptake on In-111 WBC scintigrams and bone scintigrams was smaller in 36%, equal in 55%, and greater in 9%. Factors that may help distinction of In-111 WBC uptake due to fracture alone from infection associated with fracture are discussed.