Details

Autor(en) / Beteiligte

• Sy, Kadiatou
• Flamme, Joséphine
• Maquet, Héloïse
• Chai, Feng
• Neut, Christel
• Siepmann, Florence
• Agossa, Kevimy

Titel

Antimicrobial effect and physical properties of an injectable "active oxygen" gel for the treatment of periodontitis

Ist Teil von

• American journal of dentistry, 2020-12, Vol.33 (6), p.305

Ort / Verlag

United States

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• To evaluate an injectable gel, recently proposed for the controlled release of "active oxygen" in periodontal pockets, compared to an antibiotic or an antiseptic gel, respectively. The antimicrobial activity, injectability, texture properties, swelling and water uptake of the gels were studied. The "active oxygen" gel showed a bactericidal effect comparable to the two commercially available drug products (containing minocycline or chlorhexidine) on anaerobic periodontal pathogens and did not seem to affect aerobic strains. The gel was easy to inject and stable in an aqueous medium for several days. Texture analysis revealed potential gel fragility. The investigated gel for local delivery of oxygen can help to selectively eradicate anaerobic bacteria associated with periodontitis and promote the recovery of a healthy-compatible oral flora.