Details

Autor(en) / Beteiligte

• Thien, Dao Duc
• Tai, Bui Huu
• Dai, Tran Duc
• Sa, Nguyen Hoang
• Thuy, Trinh Thi
• Hoang Anh, Nguyen Thi
• Tam, Nguyen Thanh

Titel

New phenolics from Uraria crinita (L.) DC

Ist Teil von

• Natural product research, 2022-07, Vol.36 (13), p.3381-3388

Ort / Verlag

England: Taylor & Francis

Erscheinungsjahr

2022

Quelle

Taylor & Francis

Beschreibungen/Notizen

• Reinvestigation of a methanol extract of Uraria crinita afforded a new 3- hydroxyisoflavanone, 3,5,7,2',4'-pentahydroxyisoflavanone (1), two new monoaryl glucosides, 3,4-dimethoxyphenyl 1-O-(6′-O-acetyl)-β-D-glucopyranoside (2) and 3,4,5-trimethoxyphenyl 1-O-(6′-O-acetyl)-β-D-glucopyranoside (3), in addition to three known compounds, 3′-O-methylorobol (4), robusflavone B (5), and apigenin (6). The structural elucidation of these compounds was achieved by analyses of their spectroscopic data (HR-ESI-MS, 1 D- and 2 D-NMR) and acidic hydrolysis. The U. crinita extracts and compounds 1-6 exhibited weak or no cytotoxic activity against KB, HepG2, Lu and MCF7 cell lines.