Details

Autor(en) / Beteiligte

• Zeng, Jian-Chun
• Zeng, Yi-Rong
• Li, Jie
• Feng, Wen-Jun
• Chen, Jin-Lun
• Ye, Peng-Cheng

Titel

Advances on treatment of periprosthetic infection and antibiotic delivery system after total hip arthroplasty

Ist Teil von

• Zhongguo gu shang, 2020-11, Vol.33 (11), p.1022

Ort / Verlag

China

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• Periprosthetic infection after hip replacement is a clinical catastrophic disease, which often leads to the failure of the prosthesis. It needs the combination of systemic antibiotics to cure the infection, which brings huge burden to doctors and patients. There are strict indications for debridement and one-stage revision of the prosthesis, and few cases meet the requirements. The second revision is still the gold standard for the treatment of periprosthetic infection. It is suitable for all infection conditions and has a high success rate. On the second phase of renovation, the antibiotic sustained release system plays a key role, and the carrier of antibiotic sustained-release system is the focus of current research, including classic bone cement and absorbable biomaterials. Bone cement has strong mechanical strength, but the antibiotic release shows a sharp decline trend; the absorbable biomaterials can continuously release antibiotics with high concentration, but the mechanical strength is poor, so it co