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Immunological effectiveness of secondary revaccination against tetanus performed at prolonged intervals
Ist Teil von
Žurnal mikrobiologii, ėpidemiologii i immunobiologii, 1987-06 (6), p.43
Ort / Verlag
Russia (Federation)
Erscheinungsjahr
1987
Quelle
MEDLINE
Beschreibungen/Notizen
After primary immunization with adsorbed DPT vaccine antitetanus immunity was retained for 9-10 years in 90.6-98.4% of children covered by this study. The second booster immunization of children against tetanus with adsorbed DT toxoid with reduced antigen content, made at an interval prolonged to 7-10 years under the conditions of lower antitoxic immunity, ensured a high level of intense antitetanus immunity. These data point to the possibility of prolonging the interval between booster immunizations to 9-10 years and reducing the number of injections and antigenic load.