Details

Autor(en) / Beteiligte

• Joung, Seewon
• Bergmann, Allison M
• Brown, M. Kevin

Titel

Ni-catalyzed 1,2-benzylboration of 1,2-disubstituted unactivated alkenes

Ist Teil von

• Chemical science (Cambridge), 2019-12, Vol.1 (47), p.1944-1947

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2019

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Nickel-catalyzed 1,2-carboboration of alkenes is emerging as a useful method for chemical synthesis. Prior studies have been limited to only the incorporation of aryl groups. In this manuscript, a method for the 1,2-benzylboration of unactivated alkenes is presented. The reaction combines readily available alkenes, diboron reagents and benzylchlorides to generate synthetically versatile products with control of stereochemistry. The utility of the products as well as the mechanistic details of the process are also presented. A method for the 1,2-benzylboration of unactivated alkenes is presented. The reaction combines readily available alkenes, diboron reagents and benzylchlorides to generate synthetically versatile products with control of stereochemistry.