Details

Autor(en) / Beteiligte

• Durán, Josefina
• Massardo, Loreto
• Llanos, Carolina
• Iacobelli, Sergio
• Burgos, Paula I
• Cisternas, Marcela
• Iruretagoyena, Mirentxu
• Armstrong, Macarena
• Aguilera, Raquel
• Radrigán, Francisco
• Martinez, María Eugenia
• Passi-Solar, Alvaro
• Riedemann, Pablo
• Crisóstomo, Natalia
• Cifuentes, Camila
• Hagedorn, Lucero
• Cisternas, Alvaro
• Vasquez, Nancy
• Margozzini, Paula

Titel

The Prevalence of Rheumatoid Arthritis in Chile: A Nationwide Study Performed as Part of the National Health Survey

Ist Teil von

• Journal of rheumatology, 2020-07, Vol.47 (7), p.951

Ort / Verlag

Canada

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• Genetic and environmental backgrounds influence the development of rheumatoid arthritis (RA). In Latin America, epidemiologic data are scarce. We aimed to determine the prevalence of RA in Chile in a population-based study. The National Health Survey was a cross-sectional household survey with a stratified multistage probability sample of 6233 participants performed between August 2016 and March 2017. A screening instrument for RA was applied to a random sample of 3847 subjects > 30 years old. Positive screening was defined by at least 1 of the following: 2 swollen joints for at least 4 consecutive weeks (past/present), and/or a diagnosis of arthritis in the past. Individuals with positive screening had rheumatoid factor, anticitrullinated protein antibodies, and C-reactive protein measured, as well as clinical examination performed by a rheumatologist. Self-report of doctor-diagnosed RA was also performed. The screening questionnaire was applied to 2998 subjects. A positive screening was found for 783 (22.1%). Among subjects with positive screening, 493 (66%) had a clinical evaluation performed by a rheumatologist. Using the American College of Rheumatology/European League Against Rheumatism 2010 classification criteria, prevalence was 0.6% (95% CI 0.3-1.2). Prevalence was higher in women, and 3.3% of subjects self-reported having RA. According to this national population-based study, RA prevalence in Chile is 0.6% (0.3-1.2), a value similar to what has been found in developed countries and slightly lower than some Latin American countries. Self-reporting leads to overestimating RA.