Details

Autor(en) / Beteiligte

• Hua, H J
• Li, K D
• Fang, H S
• Li, H
• Zhu, Y
• Li, X
• Song, G X
• Liu, C
• Zhang, Z H
• Fan, Q H

Titel

Clinicopathological observation of adamantinoma of long bone

Ist Teil von

• Zhonghua bing li xue za zhi, 2019-07, Vol.48 (7), p.522

Ort / Verlag

China

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the clinicopathological features and differential diagnosis of adamantinoma of long bone. Seven cases of adamantinoma on long bone were selected at Jiangsu Province People's Hospital from June 2012 to May 2018. Clinicopathologic details, immunohistochemical and molecular analysis were performed,and the relevant literature reviewed. There were 6 males and 1 female patients,age ranging from 21 to 60 years (mean 38 years). Six cases were on the right side and one case was on the left; in five cases the tumors arose from tibia, one from patella and one from humerus. Microscopically,tumour cells were mainly composed of spindle cells arranged in bundles or braids,with irregular epithelial island. Immunohistochemically,the epithelial island expressed high molecular weight cytokeratin but not CK8/18. Both epithelial and spindle components expressed vimentin. One case that was microscopically similar to intraosseous synovial sarcoma did not show SYT gene rearrangement. Clinical follow-up was available f