Natural product research, 2020-11, Vol.34 (21), p.3108-3116
2020
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Details
- Autor(en) / Beteiligte
- Titel
- Populeuphrines A and B, two new cembrane diterpenoids from the resins of Populus euphratica
- Ist Teil von
- Natural product research, 2020-11, Vol.34 (21), p.3108-3116
- Ort / Verlag
- England: Taylor & Francis
- Erscheinungsjahr
- 2020
- Quelle
- Taylor & Francis
- Beschreibungen/Notizen
- Two new cembrane diterpenoids, named populeuphrines A and B (1 and 2), together with three known analogues (3-5) were isolated from the resins of Populus euphratica. The planar structures and relative configurations of 1 and 2 were elucidated by detailed 1 D and 2 D NMR spectroscopic analyses. The absolute configurations of 1 and 2 were determined by X-ray diffraction analysis and quantum chemical computation. Biological activities of all the isolates against proliferation of human cancer cells and umbilical cord mesenchymal stem cells were evaluated.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1478-6419eISSN: 1478-6427DOI: 10.1080/14786419.2019.1610753Titel-ID: cdi_pubmed_primary_31264446
- Format
- –
- Schlagworte
- Antineoplastic Agents, Phytogenic - chemistry, Antineoplastic Agents, Phytogenic - pharmacology, Biological computing, biological evaluation, Cell Line, Tumor, Cell proliferation, Cell Proliferation - drug effects, cembrane diterpenoids, Configurations, Crystallography, X-Ray, Diterpenes, Diterpenes - chemistry, Diterpenes - isolation & purification, Diterpenes - pharmacology, Diversifolious poplar resin, Fetal Blood - cytology, Humans, Magnetic Resonance Spectroscopy, Mesenchymal Stem Cells - drug effects, Mesenchyme, Molecular Structure, NMR, Nuclear magnetic resonance, Planar structures, Polymers, Populus - chemistry, Populus euphratica, quantum chemical computation, Quantum chemistry, Resins, Resins, Plant - chemistry, Salicaceae, Stem cells, Umbilical cord, X-ray diffraction