Details

Autor(en) / Beteiligte

• Holmqvist, Viktoria
• Roos, Laura Kristine Soenderberg
• Kjartansdottir, Kristin Ros
• Dunø, Morten
• Petersen, Morten Rønn
• Hnida, Christina
• Pedersen, Inge Søkilde
• Ernst, Anja
• Toft, Christian Liebst Frisk
• Diemer, Tue
• Ingerslev, Hans Jakob
• Pinborg, Anja
• Løssl, Kristine

Titel

Preimplantation genetic testing for aneuploidy

Ist Teil von

• Ugeskrift for læger, 2019-05, Vol.181 (20)

Ort / Verlag

Denmark

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• This review summarises the current knowledge on preimplantation genetic testing for aneuploidy (PGT-A). Selection and transfer of euploid embryos aim to improve live birth rate (LBR) per embryo transfer, but fluorescence in situ hybridisation-based PGT-A and biopsy of cleavage stage embryos in the 2000s was a disappointment, as studies revealed a reduced LBR. Today, PGT-A includes comprehensive chromosome screening primarily of blastocyst biopsies. The benefit of PGT-A is highly debated: some suggest improved treatment outcome, while others claim, that the procedure is not cost-effective.