Details

Autor(en) / Beteiligte

• Kamm, Roger D.
• Bashir, Rashid
• Arora, Natasha
• Dar, Roy D.
• Gillette, Martha U.
• Griffith, Linda G.
• Kemp, Melissa L.
• Kinlaw, Kathy
• Levin, Michael
• Martin, Adam C.
• McDevitt, Todd C.
• Nerem, Robert M.
• Powers, Mark J.
• Saif, Taher A.
• Sharpe, James
• Takayama, Shuichi
• Takeuchi, Shoji
• Weiss, Ron
• Ye, Kaiming
• Yevick, Hannah G.
• Zaman, Muhammad H.

Titel

Perspective: The promise of multi-cellular engineered living systems

Ist Teil von

• APL bioengineering, 2018-12, Vol.2 (4), p.040901-040901

Ort / Verlag

United States: AIP Publishing LLC

Erscheinungsjahr

2018

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• Recent technological breakthroughs in our ability to derive and differentiate induced pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all contributed to a heightened interest in the design, assembly, and manufacture of living systems with a broad range of potential uses. This white paper summarizes the state of the emerging field of “multi-cellular engineered living systems,” which are composed of interacting cell populations. Recent accomplishments are described, focusing on current and potential applications, as well as barriers to future advances, and the outlook for longer term benefits and potential ethical issues that need to be considered.