Computer methods in biomechanics and biomedical engineering, 2019-04, Vol.22 (5), p.518-532
2019
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Details
- Autor(en) / Beteiligte
- Titel
- A methodology for numerically analysing the hepatic artery haemodynamics during B-TACE: a proof of concept
- Ist Teil von
- Computer methods in biomechanics and biomedical engineering, 2019-04, Vol.22 (5), p.518-532
- Ort / Verlag
- England: Taylor & Francis
- Erscheinungsjahr
- 2019
- Quelle
- Taylor & Francis Journals Auto-Holdings Collection
- Beschreibungen/Notizen
- Balloon-occluded transarterial chemoembolisation (B-TACE) is an intraarterial transcatheter treatment for liver cancer. In B-TACE, an artery-occluding microballoon catheter occludes an artery and promotes collateral circulation for drug delivery to tumours. This paper presents a methodology for analysing the haemodynamics during B-TACE, by combining zero-dimensional and three-dimensional modelling tools. As a proof of concept, we apply the methodology to a patient-specific hepatic artery geometry and analyse two catheter locations. Results show that the blood flow redistribution can be predicted in this proof-of-concept study, suggesting that this approach could potentially be used to optimise catheter location.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1025-5842eISSN: 1476-8259DOI: 10.1080/10255842.2019.1567720Titel-ID: cdi_pubmed_primary_30732467
- Format
- –
- Schlagworte
- 0D modelling, 3D modelling, B-TACE, Blood circulation, Blood flow, Catheters, computational fluid dynamics, Drug delivery, Drug delivery systems, haemodynamics, Hemodynamics, Hepatic artery, Liver cancer, Mathematical models, Medical instruments, Methodology, Three dimensional models, Tumors, Veins & arteries