Details

Autor(en) / Beteiligte

• Wong, K W
• D'Amico, D J
• Hedges, 3rd, T R
• Soong, H K
• Schooley, R T
• Kenyon, K R

Titel

Ocular involvement associated with chronic Epstein-Barr virus disease

Ist Teil von

• Archives of ophthalmology (1960), 1987-06, Vol.105 (6), p.788-792

Ort / Verlag

United States

Erscheinungsjahr

1987

Quelle

MEDLINE

Beschreibungen/Notizen

• Ocular involvement with acute Epstein-Barr virus infection is usually limited to a transient follicular conjunctivitis, although other lesions have been reported. Chronic Epstein-Barr virus infection has recently gained attention, but ocular manifestations have not been emphasized. We describe three patients with chronic infection with prominent ocular involvement. Bilateral uveitis was noted in all patients, ranging from an anterior uveitis that was responsive to steroids to a severe panuveitis with vitritis, cataract, optic disc swelling, and macular edema. In one patient, topical acyclovir ointment resulted in a substantial decrease in the inflammatory reaction when added to systemic acyclovir therapy. Another patient displayed a keratitis that resolved with topical steroid therapy. Cataract and vitreous surgery were also beneficial in the management of these patients.