Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1792, p.47
2018
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Deep Profiling of the Immune System of Multiple Myeloma Patients Using Cytometry by Time-of-Flight (CyTOF)
- Ist Teil von
- Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1792, p.47
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2018
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Mass cytometry has emerged as a new state-of-the-art technology that enables in-depth characterization of cellular populations and functions at a single cell resolution. We describe the application of this technology to deeply phenotype the blood and bone marrow components of multiple myeloma patients in a clinical setting. This technology allows for simultaneous quantification of more than 40 markers, overcoming the challenges of traditional fluorescence-based flow cytometry.
- Sprache
- Englisch
- Identifikatoren
- eISSN: 1940-6029DOI: 10.1007/978-1-4939-7865-6_4Titel-ID: cdi_pubmed_primary_29797251
- Format
- –
- Schlagworte
- Biomarkers, Blood Cells, Bone Marrow Cells - immunology, Bone Marrow Cells - metabolism, Flow Cytometry - methods, Humans, Immune System - immunology, Immune System - metabolism, Immunophenotyping, Multiple Myeloma - immunology, Multiple Myeloma - metabolism, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods