Details

Autor(en) / Beteiligte

• Premel-Cabic, A
• Gétin, F
• Turcant, A
• Rohmer, V
• Bigorgne, J C
• Allain, P

Titel

Plasma noradrenaline in hyperthyroidism and hypothyroidism

Ist Teil von

• La Presse médicale (1983), 1986-09, Vol.15 (32), p.1625

Ort / Verlag

France

Erscheinungsjahr

1986

Quelle

MEDLINE

Beschreibungen/Notizen

• Plasma noradrenaline concentrations (NA) were measured in 11 hypothyroid patients, 24 hypothyroid patients and 30 normal subjects after 30 minutes of supine rest and after 5 minutes of standing. Observed noradrenaline levels, after rest as well as after standing, were significantly higher in hypothyroid patients (NA rest = 0.66 +/- 0.35 microgram/l, NA standing = 1.26 +/- 0.70 micrograms/l) and significantly lower in hyperthyroid patients (NA rest = 0.22 +/- 0.13 micrograms/l, NA standing = 0.37 +/- 0.20 microgram/l) than in normal subjects (NA rest = 0.32 +/- 0.13 microgram/l, NA standing = 0.55 +/- 0.20 microgram/l). The increase in noradrenaline with standing, when expressed in percent, was similar for the three groups studied (about 100%). These results suggest that a sympathetic nervous system adaptation occurs in hyperthyroidism and hypothyroidism as a compensatory phenomenon to the direct effect of thyroid hormones on the heart.