Acta virologica (Anglickâa verze), 1978-07, Vol.22 (4), p.287
1978
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Antiviral activity of dipyridamole derivatives
- Ist Teil von
- Acta virologica (Anglickâa verze), 1978-07, Vol.22 (4), p.287
- Ort / Verlag
- Slovakia
- Erscheinungsjahr
- 1978
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Among 46 novel pyrimido [5.4-d] pyrimidine derivatives, 26 compounds were found to exhibit antiviral activity as revealed in a test programme against Mengo, Coxsackie B1, fowl plague, vaccinia and pseudorabies viruses, as concerns inhibition of plaque formation and of infectious virus yield. Attempts to disclose structure-activity relationships by discriminant analysis pointed to a possible importance of hydrophobic substitution for the antiviral effectiveness against Mengo virus of the derivatives investigated.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0001-723XeISSN: 1336-2305Titel-ID: cdi_pubmed_primary_29467
- Format
- –
- Schlagworte
- Antiviral Agents, Cell Line, Chemical Phenomena, Chemistry, Dipyridamole - analogs & derivatives, Dipyridamole - pharmacology, Enterovirus B, Human - drug effects, Herpesvirus 1, Suid - drug effects, Influenza A virus - drug effects, Mengovirus - drug effects, Newcastle disease virus - drug effects, Vaccinia virus - drug effects, Virus Replication - drug effects