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Assessment of Disease Activity in Large-vessel Vasculitis: Results of an International Delphi Exercise
Ist Teil von
Journal of rheumatology, 2017-12, Vol.44 (12), p.1928
Ort / Verlag
Canada
Erscheinungsjahr
2017
Quelle
MEDLINE
Beschreibungen/Notizen
To arrive at consensus for candidate outcomes for disease activity assessment in large-vessel vasculitis (LVV) in clinical trials.
A Delphi survey including 99 items was circulated among international experts for 3 rounds.
Fifty-seven items were accepted for both giant cell arteritis and Takayasu arteritis. Sixty-seven percent of experts voted to have a common approach for both diseases with additional disease-specific items such as weight loss, scalp tenderness/necrosis, morning stiffness, dizziness, visual symptoms, and imaging.
This study highlights similarities and differences in experts' perspectives for assessing clinical activity in LVV and may guide a consensus-driven core set of validated outcomes.