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To analyze the clinicopathological features and prognosis of patients with small hepatocellular carcinoma.
The clinicopathological and follow-up data of 98 patients with small hepatocellular carcinoma who underwent R0 resection from January 2009 to December 2013 were analyzed retrospectively.
All of the patients were followed up. Their postoperative 1-year, 3-year and 5-year overall survival rates were 99.0%, 91.7%, and 76.3%, respectively. Their postoperative median overall survival (OS) period was 52 months. The postoperative progression-free survival rates were 86.7%, 66.2% and 55.0%, respectively, and the median progression-free survival (PFS) period was 43.5 months. The univariate analysis showed that satellite nodules, liver capsule invasion and postoperative recurrence time were associated with OS (
<0.05), and long-term heavy drinking, satellite nodules and liver capsule invasion with PFS (
<0.05). The multivariate analysis indicated that long-term heavy drinking was an independent factor influencing