Details

Autor(en) / Beteiligte

• Yin, Yue
• Qiu, Zhi-Xiang
• Li, Yuan
• Xu, Wei-Lin
• Sun, Yu-Hua
• Liu, Wei
• Wang, Wen-Sheng
• Wang, Mang-Ju
• Wang, Li-Hong
• Dong, Yu-Jun
• Ou, Jin-Ping
• Cen, Xi-Nan
• Ren, Han-Yun

Titel

Salvage Trerapy for Patients with Relapsed and Refractory Lymphoma by Allogeneic Hematopoietic Stem Cell Transplantation

Ist Teil von

• Zhongguo shi yan xue ye xue za zhi, 2017-04, Vol.25 (2), p.418

Ort / Verlag

China

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• To assess the safety and efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in treating patients with relapsed and refractory lymphoma. Thirty-one consecutive patients with relapsed or refractory lymphoma received allo-HSCT. Used conditioning regimens included conditioning based on BEAM regimen(12 cases), conditioning based on modified Bu/Cy regimen(11 cases), conditioning based on Cy/TBI regemen(6 cases) and conditioning of Bu/Cy regimen(1 case). For provention of GVHD, the MMF was used on the basis of classcal protocol consisting of CsA combined with MTX. The infused HSC included the HLA-matched related HSC(11 cases), HLA nonidentical related HSC(13 cases) and HLA-matched unrelated HSC(6 cases). The bone marrow plus peripheral blood HSC were infused in 21 cases, while only peripheral blood HSC were infused in 9 cases. Among the 31 cases of relapse/refractory lymphoma, 18 patients were male and 13 were female, 4 cases were Hodgkin's lymphoma and 27 cases were non-Hodgkin's lymphoma. A