Details

Autor(en) / Beteiligte

• Wang, Dan
• Bi, Ya-Wei
• Ji, Jun-Tao
• Xin, Lei
• Pan, Jun
• Liao, Zhuan
• Du, Ting-Ting
• Lin, Jin-Huan
• Zhang, Di
• Zeng, Xiang-Peng
• Ye, Bo
• Zou, Wen-Bin
• Chen, Hui
• Xie, Ting
• Li, Bai-Rong
• Zheng, Zhao-Hong
• Li, Zhao-Shen
• Hu, Liang-Hao

Titel

Extracorporeal shock wave lithotripsy is safe and effective for pediatric patients with chronic pancreatitis

Ist Teil von

• Endoscopy, 2017-05, Vol.49 (5), p.447-455

Ort / Verlag

Germany

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is recommended as the first-line treatment for pancreatic stones. However, how well P-ESWL performs in pediatric patients remains unclear. We aimed to evaluate the safety and efficacy of P-ESWL for pediatric patients with chronic pancreatitis. This prospective observational study was conducted in patients with painful chronic pancreatitis who underwent P-ESWL. Patients aged under 18 years were included in the pediatric group; patients aged over 18 years who underwent P-ESWL in the same period were assigned to the control group. For investigation of long-term follow-up, the pediatric group were matched with patients from the control group in a 1:1 ratio. The primary outcomes were P-ESWL complications and pain relief. The secondary outcomes included: stone clearance, physical and mental health, quality of life score, and growth and developmental state. From March 2011 to March 2015, P-ESWL was performed in 1135 patients (72 in the pediatric group, 1063 in the control group). No significant differences were observed in the occurrence of P-ESWL complications between the two groups (11.1 % vs. 12.8 %;  = 0.68). Among the 67 pediatric patients (93.1 %) who underwent follow-up for 3.0 years (range 1.3 - 5.2), complete pain relief was achieved in 52 patients (52 /67; 77.6 %); this value was not significantly different from that of the matched controls (55 /69; 79.7 %;  = 0.94). P-ESWL is safe and effective for pediatric patients with chronic pancreatitis. It can promote significant pain relief and stone clearance, and can benefit growth and development.