Details

Autor(en) / Beteiligte

• Iakusheva, L A
• Nagaev, I Iu
• Lazurkina, T Iu
• Shevchenko, V P
• Miagkova, G I

Titel

Directed biosynthesis of prostaglandin F2 alpha multiple labeled with tritium

Ist Teil von

• Bioorganicheskaia khimiia, 1988-02, Vol.14 (2), p.232

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

1988

Quelle

MEDLINE

Beschreibungen/Notizen

• By selecting specific activators of PGF reductase and determining their optimal ratio, we have performed the directed biosynthesis of PGF2 alpha with a 45-50% yield. With the use of [5,6,8,9,11,12,14,15-3H8]arachidonic acid, multiple-labelled PGF2 alpha with molar radioactivity 6.1 TBe/mmol has been synthesised.