Natural product research, 2017-07, Vol.31 (14), p.1676-1681
2017
Details
- Autor(en) / Beteiligte
- Titel
- A new sesquiterpene lactone from fungus Eutypella sp. D-1
- Ist Teil von
- Natural product research, 2017-07, Vol.31 (14), p.1676-1681
- Ort / Verlag
- England: Taylor & Francis
- Erscheinungsjahr
- 2017
- Link zum Volltext
- Quelle
- Taylor & Francis Online
- Beschreibungen/Notizen
- We isolated and identified a new sesquiterpene lactone which we named eut-Guaiane sesquiterpene (1), along with four cytochalasins from the fungus Eutypella sp. derived from the soil of high latitude of Arctic. The new structure was determined by spectroscopic studies such as 1D and 2D NMR and MS analyses, while the known compounds were identified by comparison of the NMR data with those in literatures. New compound 1 exhibited strong antibacterial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus. Besides, it showed a little cytotoxicity against SGC7901 cell line.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1478-6419eISSN: 1478-6427DOI: 10.1080/14786419.2017.1286486Titel-ID: cdi_pubmed_primary_28278679
- Format
- –
- Schlagworte
- Anti-Bacterial Agents - chemistry, Anti-Bacterial Agents - isolation & purification, Antibacterial activity, Antibacterial materials, Ascomycota - chemistry, Bacillus subtilis - drug effects, Cytotoxicity, E coli, Escherichia coli - drug effects, Eutypella sp, Fungi, Lactones - isolation & purification, Magnetic Resonance Spectroscopy, Molecular Structure, NMR, Nuclear magnetic resonance, Polar environments, sesquiterpene lactone, Sesquiterpenes - chemistry, Sesquiterpenes - isolation & purification, Sesquiterpenes, Guaiane, Spectroscopic analysis, Staphylococcus aureus - drug effects, Toxicity