Arteriosclerosis, thrombosis, and vascular biology, 2017-01, Vol.37 (1), p.35
2017
Details
- Autor(en) / Beteiligte
- Titel
- Monocyte Conversion During Inflammation and Injury
- Ist Teil von
- Arteriosclerosis, thrombosis, and vascular biology, 2017-01, Vol.37 (1), p.35
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2017
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Monocytes are circulating leukocytes important in both innate and adaptive immunity, primarily functioning in immune defense, inflammation, and tissue remodeling. There are 2 subsets of monocytes in mice (3 subsets in humans) that are mobilized from the bone marrow and recruited to sites of inflammation, where they carry out their respective functions in promoting inflammation or facilitating tissue repair. Our understanding of the fate of these monocyte subsets at the site of inflammation is constantly evolving. This brief review highlights the plasticity of monocyte subsets and their conversion during inflammation and injury.
- Sprache
- Englisch
- Identifikatoren
- eISSN: 1524-4636DOI: 10.1161/atvbaha.116.308198Titel-ID: cdi_pubmed_primary_27765768
- Format
- –
- Schlagworte
- Animals, Cell Plasticity, Chemotaxis, Leukocyte, Hemostasis, Humans, Inflammation - immunology, Inflammation - metabolism, Inflammation - pathology, Inflammation Mediators - immunology, Inflammation Mediators - metabolism, Macrophages - immunology, Macrophages - metabolism, Macrophages - pathology, Mice, Monocytes - classification, Monocytes - immunology, Monocytes - metabolism, Monocytes - pathology, Phenotype, Signal Transduction, Wound Healing