Details

Autor(en) / Beteiligte

• Ruiz-Medrano, Jorge
• Flores-Moreno, Ignacio
• Peña-García, Pablo
• Montero, Javier A
• García-Feijóo, Julián
• Duker, Jay S
• Ruiz-Moreno, José M

Titel

ANALYSIS OF AGE-RELATED CHOROIDAL LAYERS THINNING IN HEALTHY EYES USING SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

Ist Teil von

• Retina (Philadelphia, Pa.), 2017-07, Vol.37 (7), p.1305

Ort / Verlag

United States

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• To study the changes in the choroidal layers thickness with age in a healthy population using swept-source optical coherence tomography. Retrospective data analysis of a subgroup of eyes from a previous single-center, prospective, cross-sectional, noninterventional study. One hundred and sixty-nine healthy eyes were evaluated using swept-source optical coherence tomography. Inclusion criteria were best-corrected visual acuity between 20/20 and 20/25, spherical equivalent between ±3 diopters, and no systemic or ocular diseases. Two independent investigators determined the macular horizontal choroidal thickness (CT) and the Haller's layer thickness across a 9 mm line centered at the fovea. Subjects were divided into five age groups. Mean subfoveal choroidal thickness was 305.76 ± 80.59 μm (95% confidence interval: 294.85-319.33). Mean subfoveal thickness for Haller's layer was 215.47 ± 67.70 μm (95% confidence interval: 207.30-227.86) and mean subfoveal thickness for choriocapillaris plus Sattler's layer was 87.31 ± 40.40 μm (95% confidence interval: 83.38-95.65). No significant differences were found due to gender. Choroidal thickness profile was similar between groups with choroidal thickness and Haller's layer thickness decreasing with age (P = 0.002). Choroidal and Haller's layer thickness profiles are similar between different age groups. Age-related choroidal thinning is mostly at the expense of Haller's layer.