Voprosy meditsinskoi khimii, 1989-01, Vol.35 (1), p.92
1989
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Details
- Autor(en) / Beteiligte
- Titel
- Activity of lysosomal hydrolases and renewal of proteins in the rat liver, spleen, and thymus during antigenic stimulation and protein deficiency
- Ist Teil von
- Voprosy meditsinskoi khimii, 1989-01, Vol.35 (1), p.92
- Ort / Verlag
- Russia (Federation)
- Erscheinungsjahr
- 1989
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Activity of cathepsins B and C was increased 1.8-2-fold in spleen simultaneously with a decrease 3.8-fold in the rate of protein renewal in the tissue lysosomal fraction within 4 days after antigen stimulation of rats, maintained within 45 days on a diet containing 5% of protein. Activation of these thiol-dependent proteinases appears to occur in response to development of immunodepressive conditions and may be related to alterations in the rate of their biosynthesis.
- Sprache
- Russisch
- Identifikatoren
- ISSN: 0042-8809Titel-ID: cdi_pubmed_primary_2741402
- Format
- –
- Schlagworte
- Animals, Antigens - immunology, Cathepsin B - metabolism, Cathepsin C, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism, Half-Life, Hydrolases - metabolism, Immunization, Liver - metabolism, Lysosomes - enzymology, Male, Protein Deficiency - metabolism, Proteins - metabolism, Rats, Rats, Inbred Strains, Spleen - metabolism, Subcellular Fractions - analysis, Thymus Gland - metabolism