Details

Autor(en) / Beteiligte

• Bhattarai, Yogesh
• Kashyap, Purna C

Titel

Germ-Free Mice Model for Studying Host-Microbial Interactions

Ist Teil von

• Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1438, p.123

Ort / Verlag

United States

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Germ-free (GF) mice are a relevant model system to study host-microbial interactions in health and disease. In this chapter, we underscore the importance of using GF mice model to study host-microbial interactions in obesity, immune development and gastrointestinal physiology by reviewing current literature. Furthermore, we also provide a brief protocol on how to setup a gnotobiotic facility in order to properly maintain and assess GF status in mice colonies.