Guang pu xue yu guang pu fen xi, 2015-11, Vol.35 (11), p.3054
2015
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- Autor(en) / Beteiligte
- Titel
- The Study on the Far-FTIR and THz Spectra of Azitromycin Drugs with Different Physical Forms
- Ist Teil von
- Guang pu xue yu guang pu fen xi, 2015-11, Vol.35 (11), p.3054
- Ort / Verlag
- China
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Far Fourier transform infrared spectroscopy (Far-FTIR) and terahertz time-domain spectroscopy (THz-TDS) were used to measure the fingerprint spectra of Azitromycin suspension, capsule, tablet and dispersible tablet under vacuum and nitrogen conditions, respectively. In the frequency range of 0.2-15 THz, highly resolved spectral features for Azitromycin suspension were measured and some minor differences were observed between domestic and exotic Azitromycin Suspension, such as linewidth broadening and additional peaks. As same time, for the domestic Azitromycin capsule, tablet and dispersible tablet, the absorption baselines in the range of 0.2-2.7 THz rise with the increase of frequency while absorption peaks become weaker due to the scattering of bigger particles and smaller amount of Azitromycin. Also, the additional peaks are caused by the absorption of filling materials. In parallel with the qualitative measurement, the THz absorption spectra for mixtures of polyethylene (PE) powders and exotic Azithomyci
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 1000-0593DOI: 10.3964/j.issn.1000-0593(2015)11-3054-04Titel-ID: cdi_pubmed_primary_26978907