Details

Autor(en) / Beteiligte

• Conejo Moreno, David
• Rodríguez Fernández, Cristina
• Ruíz Ayúcar de la Vega, Irene
• Ortiz Madinaveitia, Saturnino
• Hedrera Fernández, Antonio
• Maldonado Ruiz, Esther
• Hernández Fabian, Aranzazu
• Hortigüela Saeta, María Montesclaros
• Cancho Candela, Ramón

Titel

Para-infectious seizures: A retrospective multicentre study

Ist Teil von

• Anales de pediatría (Barcelona, Spain : 2003), 2016-12, Vol.85 (6), p.300

Ort / Verlag

Spain

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Para-infectious seizures are afebrile seizures that are associated with mild infections, and occur in children with no pre-existing neurological illness. They are still little known in our environment. A multicentre retrospective study was conducted that included patients with normal psychomotor development and had presented with one or more seizures in the context of a mild afebrile infection. A total of 38 patients (47% male, 53% female) were included in the study over a period of three years (2012-2015). The mean age was 2.1 years. A previous history of febrile seizures was found in 7.9% of them. Mean number of seizures per patient was 2.2, with 57.9% of them being tonic-clonic seizures. The mean duration of seizures was 3.2minutes. An EEG was performed during admission in 73.7% of cases. Lumbar punctures were performed in 34.2% of cases. All were normal. Neuroimaging tests were carried out in 36.9% of cases. Brain MRI was the imaging test performed in most cases (21.1%), with no any pathological findings. The most frequent infection found was acute gastroenteritis (68%), followed by upper respiratory tract infection (32%). Almost two-thirds (63.2%) of patients did not require anticonvulsant medication. Rectal diazepam was the most frequently used drug in emergencies. Intravenous medication was required by 28.9% of patients due to repeated seizures. The most frequently used drug in the non-emergency setting was valproic acid. Anticonvulsant treatment was continued after discharge in 16% of patients. Para-infectious seizures was the diagnosis in 76.3% of cases when discharged. Knowledge of para-infectious seizures, their clinical diagnosis and benign course is crucial, as this would avoid further testing and unnecessary treatments.