Details

Autor(en) / Beteiligte

• Rosenberg, Monica D
• Finn, Emily S
• Scheinost, Dustin
• Papademetris, Xenophon
• Shen, Xilin
• Constable, R Todd
• Chun, Marvin M

Titel

A neuromarker of sustained attention from whole-brain functional connectivity

Ist Teil von

• Nature neuroscience, 2016-01, Vol.19 (1), p.165

Ort / Verlag

United States

Erscheinungsjahr

2016

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Although attention plays a ubiquitous role in perception and cognition, researchers lack a simple way to measure a person's overall attentional abilities. Because behavioral measures are diverse and difficult to standardize, we pursued a neuromarker of an important aspect of attention, sustained attention, using functional magnetic resonance imaging. To this end, we identified functional brain networks whose strength during a sustained attention task predicted individual differences in performance. Models based on these networks generalized to previously unseen individuals, even predicting performance from resting-state connectivity alone. Furthermore, these same models predicted a clinical measure of attention--symptoms of attention deficit hyperactivity disorder--from resting-state connectivity in an independent sample of children and adolescents. These results demonstrate that whole-brain functional network strength provides a broadly applicable neuromarker of sustained attention.