Details

Autor(en) / Beteiligte

• Bachmann, H
• Lössner, J
• Kühn, H J
• Biesold, D
• Siegemund, R
• Kunath, B
• Willgerodt, H
• Teichmann, B
• Wieczorek, V
• Mühlau, G

Titel

Long-term care and management of Wilson's disease in the GDR

Ist Teil von

• European neurology, 1989, Vol.29 (6), p.301

Ort / Verlag

Switzerland

Erscheinungsjahr

1989

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Diagnosis, long-term management and family investigations of Wilson's disease are provided by selected clinical institutions in the GDR. From 187 patients detected since 1949, 111 are alive. In spite of the principal effectiveness of penicillamine treatment, confirmed by the disappearance of most of the central nervous system symptoms and successful professional rehabilitation of many patients, insufficient therapeutic discipline, psychosocial disturbances and penicillamine side-effects forcing its substitution by zinc or triethylenetetramine dihydrochloride in 14 cases need our further attention.