JAMA ophthalmology, 2015-05, Vol.133 (5), p.598
2015
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Genetic testing for age-related macular degeneration: not indicated now
- Ist Teil von
- JAMA ophthalmology, 2015-05, Vol.133 (5), p.598
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Age-related macular degeneration is a very common condition that is caused by a complex interplay of genetic and environmental factors. It is likely that, in the future, genetic testing will allow physicians to achieve better clinical outcomes by administering specific treatments to patients based on their genotypes. However, improved outcomes for genotyped patients have not yet been demonstrated in a prospective clinical trial, and as a result, the costs and risks of routine genetic testing currently outweigh the benefits for patients with age-related macular degeneration.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2168-6165eISSN: 2168-6173DOI: 10.1001/jamaophthalmol.2015.0369Titel-ID: cdi_pubmed_primary_25789813
- Format
- –
- Schlagworte
- Academies and Institutes, Aged, Aged, 80 and over, Complement Factor H - genetics, Genetic Predisposition to Disease, Genetic Testing, Humans, Macular Degeneration - genetics, Ophthalmology - organization & administration, Practice Guidelines as Topic, Prospective Studies, Proteins - genetics, Risk Assessment