Current topics in medicinal chemistry, 2015-01, Vol.15 (3), p.223-244
2015
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Details
- Autor(en) / Beteiligte
- Titel
- Sol-gel encapsulation of biomolecules and cells for medicinal applications
- Ist Teil von
- Current topics in medicinal chemistry, 2015-01, Vol.15 (3), p.223-244
- Ort / Verlag
- United Arab Emirates
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The sol-gel process provides a robust and versatile technology for the immobilization of biologicals. A wide range of inorganic, composites and hybrid materials can be prepared to encapsulate molecular drugs, proteins, antibodies/antigens, enzymes, nucleic acids, prokaryotic and eukaryotic cells into bulk gels, particles and films. This review describes the applications of sol-gel encapsulation relevant to medicinal chemistry focusing on the recent development of biosensors as well as systems for production, screening and delivery of bioactive compounds and biomaterials.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1568-0266eISSN: 1873-4294DOI: 10.2174/1568026614666141229112734Titel-ID: cdi_pubmed_primary_25547970
- Format
- –
- Schlagworte
- Animals, Anti-Bacterial Agents - chemistry, Anti-Bacterial Agents - metabolism, Biosensing Techniques - methods, Cells, Immobilized, Chemistry, Pharmaceutical - methods, Delayed-Action Preparations, Drug Carriers - chemical synthesis, Drug Carriers - chemistry, Drug Compounding - methods, Gels, Humans, Immobilized Proteins - chemistry, Nanoparticles - chemistry, Phase Transition, Silicon Dioxide - chemistry, Tissue Engineering