Details

Autor(en) / Beteiligte

• Hejazian, Majid
• Li, Weihua
• Nguyen, Nam-Trung

Titel

Lab on a chip for continuous-flow magnetic cell separation

Ist Teil von

• Lab on a chip, 2015-01, Vol.15 (4), p.959-97

Ort / Verlag

England

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the various methods, magnetic separation of cells utilizing microfluidic devices offers the merits of biocompatibility, efficiency, and simplicity. This review discusses the fundamental physics involved in using magnetic force to separate particles, and identifies the optimisation parameters and corresponding methods for increasing the magnetic force. The paper then elaborates the design considerations of LOC devices for continuous-flow magnetic cell separation. Examples from the recently published literature illustrate these state-of-the-art techniques. We review the fundamental physics in continuous-flow magnetic cell separation and identify the optimisation parameters of LOC devices.