Details

Autor(en) / Beteiligte

• Gan'shina, T S
• Kim, G A
• Gnezdilova, A V
• Gorbunov, A A
• Mirzoian, R S

Titel

Comparative study of the effect of S-amlodipine nicotinate and amlodipine benzylate on the arterial pressure of awake rats

Ist Teil von

• Ėksperimentalʹnaâ i kliničeskaâ farmacologiâ, 2014, Vol.77 (8), p.20

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• We have performed a comparative study of the effects of two calcium channel blockers, S-amlodipine nicotinate and amnlodipine benzylate, on the arterial pressure (AP) of awake rats measured in the tail artery. The results of experiments showed that both preparations produce a statistically significant long-term decrease in the AP of animals. In respect of both strength and duration of the hypotensive effect, S-amlodipine nicotinate somewhat exceeds amnlodipine benzylate.