Details

Autor(en) / Beteiligte

• Kariminia, Azar
• Durier, Nicolas
• Jourdain, Gonzague
• Saghayam, Suneeta
• Do, Chau V
• Nguyen, Lam Van
• Hansudewechakul, Rawiwan
• Lumbiganon, Pagakrong
• Chokephaibulkit, Kulkanya
• Truong, Khanh Huu
• Sirisanthana, Virat
• Ung, Vibol
• Vonthanak, Saphonn
• Ananworanich, Jintanat
• Nik Yusoff, Nik Khairulddin
• Kurniati, Nia
• Azahar Razali, Kamarul
• Fong, Moy Siew
• Nallusamy, Revathy
• Wati, Dewi Kumara

Titel

Weight as predictors of clinical progression and treatment failure: results from the TREAT Asia Pediatric HIV Observational Database

Ist Teil von

• Journal of acquired immune deficiency syndromes (1999), 2014-09, Vol.67 (1), p.71-76

Ort / Verlag

United States

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• To evaluate the value of time-updated weight and height in predicting clinical progression, and immunological and virological failure in children receiving combination antiretroviral therapy (cART). We used Cox regression to analyze data of a cohort of Asian children. A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score < -3 was associated with mortality (P < 0.001) independent of CD4% and < -2 was associated with immunological failure (P ≤ 0.03) independent of age at cART. Weight monitoring provides useful data to inform clinical management of children on cART in resource-limited settings.