Details

Autor(en) / Beteiligte

• Miao, Rong-ming
• Ding, Bang-mei
• Zhang, Xue-tao
• Fang, Zhong-hua
• Zhao, Rui
• Zhang, Ying-yi
• Zhao, Dao-kun

Titel

Changes in activities of SOD and GSH-Px in induced sputum and their significance among silicosis patients

Ist Teil von

• Zhonghua laodong weisheng zhiyebing zazhi, 2013-12, Vol.31 (12), p.924

Ort / Verlag

China

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• To observe the changes in activities of superoxide dismutase (SOD) and glutathione peroxide (GSH-Px) in the induced sputum of silicosis patients, and to investigate the roles of SOD and GSH-Px in the development and progression of silicosis and the significance of measuring activities of SOD and GSH-Px in induced sputum among silicosis patients. Fifty hotel attendants were chosen as control group, 50 workers with more than one year of silica dust exposure as dust exposure group, 32 silica dust-exposed workers as observation subject group, and 52 silicosis patients as silicosis group. The activities of SOD and GSH-Px in their induced sputum were measured by enzyme-linked immunosorbent assay. Compared with the control group, the observation subject group and silicosis group had significantly decreased SOD activity (68.16 ± 30.17 and 66.38 ± 47.32 U/ml vs 75.81 ± 11.92 U/ml, P < 0.05); compared with the dust exposure group, the silicosis group had significantly decreased SOD activity (66.38 ± 47.32 U/ml vs 70.12