Nature cell biology, 2014-01, Vol.16 (1), p.66-76
2014
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- Autor(en) / Beteiligte
- Titel
- A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development
- Ist Teil von
- Nature cell biology, 2014-01, Vol.16 (1), p.66-76
- Ort / Verlag
- England
- Erscheinungsjahr
- 2014
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The phytohormone auxin is a key developmental signal in plants. So far, only auxin perception has been described to trigger the release of transcription factors termed Auxin Response Factors (ARFs) from their auxin/indole-3-acetic acid (AUX/IAA) repressor proteins. Here, we show that phosphorylation of ARF7 and ARF19 by BRASSINOSTEROID-insensitive2 (BIN2) can also potentiate auxin signalling output during lateral root organogenesis. BIN2-mediated phosphorylation of ARF7 and ARF19 suppresses their interaction with AUX/IAAs, and subsequently enhances the transcriptional activity to their target genes lateral organ boundaries-domain16 (LBD16) and LBD29. In this context, BIN2 is under the control of the Tracheary element differentiation inhibitory factor (TDIF)-TDIF receptor (TDR) module. TDIF-initiated TDR signalling directly acts on BIN2-mediated ARF phosphorylation, leading to the regulation of auxin signalling during lateral root development. In summary, this study delineates a TDIF-TDR-BIN2 signalling cascade that controls regulation of ARF and AUX/IAA interaction independent of auxin perception during lateral root development.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1465-7392eISSN: 1476-4679DOI: 10.1038/ncb2893Titel-ID: cdi_pubmed_primary_24362628
- Format
- –
- Schlagworte
- Amino Acid Sequence, Arabidopsis - drug effects, Arabidopsis - genetics, Arabidopsis - growth & development, Arabidopsis Proteins - chemistry, Arabidopsis Proteins - genetics, Arabidopsis Proteins - metabolism, Arabidopsis Proteins - pharmacology, DNA, Plant - metabolism, Gene Expression Regulation, Plant - drug effects, Indoleacetic Acids - pharmacology, Models, Biological, Molecular Sequence Data, Mutation - genetics, Oligopeptides - pharmacology, Phosphorylation - drug effects, Plant Roots - drug effects, Plant Roots - genetics, Plant Roots - growth & development, Protein Binding - drug effects, Protein Binding - genetics, Protein Kinases - metabolism, Signal Transduction, Transcription Factors - chemistry, Transcription Factors - genetics, Transcription Factors - metabolism, Transcription, Genetic - drug effects