Details

Autor(en) / Beteiligte

• Nose, Hirofumi
• Kitamura, Shunji
• Nishikawa, Tatto

Titel

A virtual respiratory model of the concentration of each gas in the alveoli as a function of time when the inspired and expired volumes are equal

Ist Teil von

• Masui. The Japanese journal of anesthesiology, 2013-10, Vol.62 (10), p.1257

Ort / Verlag

Japan

Erscheinungsjahr

2013

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• A specific mathematical ventilation model was assumed to derive a new expression for the concentration of each gas in the alveoli with only the ventilatory parameters or with the functional residual volume, tidal volume, anatomical dead space, and end-tidal gas concentration. The inequality derived from the mean concentration equation showed that, if the I to E ratio was inversed, the end-tidal P(CO2) was higher than the mean alveolar P(CO2), which was almost equal to the sampled arterial P(CO2). In the present model, at the inverse ratio ventilation (IRV), the end-tidal P(CO2) was higher than the arterial P(CO2). The mean equation provided not only the A-a D(O2), but also the a-AD(CO2). The A-aD(O2) was evaluated with respect to cardiac output. In the equation, I is the duration of inspiration; E is the duration of expiration; P(CO2) is the carbon dioxide tension; A-aD(O2) is the mean alveolar/mean arterial P(O2) difference; P(O2) is the oxygen tension; and a-AD(CO2) is the mean arterial/mean alveolar P(CO2) difference.