Details

Autor(en) / Beteiligte

• Zhu, Xiaoling
• Chen, Hongxiao
• Cai, Longfeng
• Yu, Zhiming
• Cai, Limin

Titel

Decrease recurrence rate of condylomata acuminata by photodynamic therapy combined with CO2 laser in mainland China: a meta-analysis

Ist Teil von

• Dermatology (Basel), 2012-01, Vol.225 (4), p.364-370

Ort / Verlag

Switzerland

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Condylomata acuminata (CA) are caused by human papillomavirus. Most conventional therapies for CA have high recurrence rate. To compare the recurrence rate of 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser and CO2 laser alone for CA treatment in mainland China. In this meta-analysis, 2,048 cases of CA from 22 articles were divided into two groups. The treatment group was treated by using ALA-PDT combined with CO2 laser, and CO2 laser alone was applied in the control group. The recurrence rate of the two groups was calculated and compared. The recurrence rate was 42.67% (451/1,057) in the control group and 10.29% (102/991) in the treatment group, with a significant statistical difference between the two groups (χ(2) = 271.98, p < 0.0001). ALA-PDT combined with CO2 laser was more effective in decreasing the recurrence rate of CA compared with CO2 laser alone. It might offer a wide clinical application for CA treatment.