Shanghai kou qiang yi xue, 2012-12, Vol.21 (6), p.606
2012
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- Autor(en) / Beteiligte
- Titel
- The change of calcitonin gene- related peptide in periodontal tissue during orthodontic tooth movement
- Ist Teil von
- Shanghai kou qiang yi xue, 2012-12, Vol.21 (6), p.606
- Ort / Verlag
- China
- Erscheinungsjahr
- 2012
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- To establish a Sprague-Dawley rat model of tooth movement, detect the expression of calcitonin gene-related peptide (calcitonin gene related peptide, CGRP) in Sprague-Dawley rats' periodontal tissues during tooth movement and explore the role of the peripheral mechanisms of pain in orthodontics. 60 Sprague-Dawley rats were randomly divided into experimental group (n=54) and control group (n=6). Force was applied on right maxillary first molar in rats and the changes of CGRP expression were detected by real-time PCR 4 h, 8 h, 1 d, 3 d, 5 d, 7 d, 14 d after tooth movement. SPSS 13.0 software package was selected and one-way ANOVA (least significant difference, LSD) was used for statistics analysis. Experimental tooth movement led to an increase in the expression of CGRP. In addition, following experimental tooth movement, the expression of CGRP in periodontal tissues was significantly up-regulated from 4 h, with a peak on 1d and returned to the control level at 2-week. 1 d after experimental tooth movement, the
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 1006-7248Titel-ID: cdi_pubmed_primary_23364540
- Format
- –
- Schlagworte
- Animals, Calcitonin, Calcitonin Gene-Related Peptide, Maxilla, Molar, Periodontal Ligament, Periodontium, Rats, Rats, Sprague-Dawley, Tooth Movement Techniques