Details

Autor(en) / Beteiligte

• Liu, Jia
• Cui, Wei-guo
• Xue, Xiu-juan
• Sun, Guo-qing
• Tian, Sui-an
• Liu, Chun-hua
• Cheng, Yao-wu
• Wang, Zhe

Titel

Follow-up study on 84 AIDS patients having received the replaced therapy program for six months in one county of Henan, China

Ist Teil von

• Zhōnghuá liúxíngbìng zázhì, 2012-09, Vol.33 (9), p.893

Ort / Verlag

China

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• To analyze the situation of AIDS patients who had received replaced therapy program in Henan province. 84 AIDS patients had been enrolled into the national free first-line antiretroviral treatment for more than 5 years and would soon be replaced with another antiretroviral treatment program, were selected to a follow-up program to be carried out six months later. Data on CD4(+) t-lymphocyte count, viral load and genotypic resistance were included in the study. The DDI+AZT+NVP treatment program was used by all the 84 patients at baseline. A replacement by 3TC + AZT + NVP (post first-line) in 31 patients and 3TC + TDF + LPV/r (second-line) in another 53 patients were taken place within a week. All the patients were followed for six months. showed that: all of the 84 patients appeared an amelioration of CD4(+) t-lymphocyte count median from the baseline of 374.00 cell/µl to 406.50 cell/µl (P = 0.005). Those patients who had changed to second-line treatment program also showed an improvement of CD4(+) t-lymphocyt