Details

Autor(en) / Beteiligte

• Isea-Peña, M C
• Brezmes-Valdivieso, M F
• González-Velasco, M C
• Lezcano-Carrera, M A
• López-Urrutia-Lorente, L
• Martín-Casabona, N
• Monforte-Cirac, M L
• Palacios, J J
• Penedo-Pallares, A
• Ramirez-Rosales, A
• Sánchez-Silos, R
• Tórtola-Fernández, T
• Viñuelas-Bayón, J
• Vitoria-Agreda, A
• Esteban, J

Titel

Mycobacterium africanum, an emerging disease in high-income countries?

Ist Teil von

• The international journal of tuberculosis and lung disease, 2012-10, Vol.16 (10), p.1400-1404

Ort / Verlag

France

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Mycobacterium africanum is a cause of tuberculosis (TB) that has mainly been described in Africa, but immigration and travel patterns have contributed to the spread of the disease to other countries. We retrospectively reviewed TB cases due to M. africanum during 2000-2010 in seven Spanish hospitals. Selected clinical charts were reviewed using a predefined protocol that included demographical, clinical and microbiological data and outcome. Although 57 cases were diagnosed, only 36 clinical charts were available for review: 82.8% were men and the mean age was 31.6 years (range 12-81). Forty-four cases were from Africa, 1 from the Philippines, 1 from India, and 4 from Spain, while the country of origin was unknown in 7 cases. The most frequent site of infection was the lung (58.3%). Four cases (6.9%) were resistant to at least one first-line anti-tuberculosis drug. Disease due to M. africanum in industrialised countries is mainly associated with immigration from endemic areas, although some cases also occur among native-born populations.