Details

Autor(en) / Beteiligte

• Krylova, N V
• Popov, A M
• Leonova, G N
• Artiukov, A A
• Maĭstrovskaia, O S

Titel

Comparative study of antiviral activity of luteolin and 7,3'-disulfate luteolin

Ist Teil von

• Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Vol.56 (11-12), p.7

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

2011

Link zum Volltext

Beschreibungen/Notizen

• Antiviral activity of 7,3'-disulfate luteolin, extracted from Zostera marina was studied on an experimental model of tick-borne encephalitis (TBE) in vivo and in vitro. The drug increased the survival of the experimental mice infected with TBE virus and prolonged their lifespan. It was shown that 7,3'-disulfate luteolin reduced the virus accumulation in the SPEV cells by 2.0-4.0 lg TCID50/ml.