Details

Autor(en) / Beteiligte

• Limson, B M
• Chan, V F
• Guzman, S V
• Maaba, M R
• Mendoza, M T

Titel

Occurrence of infection with group B coxsackievirus in rheumatic and nonrheumatic Filipino children

Ist Teil von

• The Journal of infectious diseases, 1979-09, Vol.140 (3), p.415

Ort / Verlag

United States

Erscheinungsjahr

1979

Quelle

MEDLINE

Beschreibungen/Notizen

• The pathogenesis of rheumatic fever has been linked to various immune mechanisms involving streptococcal antibodies and heart tissue antigens. Latent myocarditis due to group B coxsackievirus has also been considered as a possible conditioning factor. The validity of the role of infection with group B coxsackievirus in rheumatic fever was tested by determining the incidence of type-specific neutralizing antibodies in sera of Filipino children. Analysis of the results by means of a normal Z-test showed that the incidence in rheumatic children was not statistically significant in comparison to the incidence in asymptomatic children.