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Occurrence of infection with group B coxsackievirus in rheumatic and nonrheumatic Filipino children
Ist Teil von
The Journal of infectious diseases, 1979-09, Vol.140 (3), p.415
Ort / Verlag
United States
Erscheinungsjahr
1979
Quelle
MEDLINE
Beschreibungen/Notizen
The pathogenesis of rheumatic fever has been linked to various immune mechanisms involving streptococcal antibodies and heart tissue antigens. Latent myocarditis due to group B coxsackievirus has also been considered as a possible conditioning factor. The validity of the role of infection with group B coxsackievirus in rheumatic fever was tested by determining the incidence of type-specific neutralizing antibodies in sera of Filipino children. Analysis of the results by means of a normal Z-test showed that the incidence in rheumatic children was not statistically significant in comparison to the incidence in asymptomatic children.