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Immunohistochemical study of adhesive molecules Her-2/neu in nonendometrial carcinoma of corpus uteri
Ist Teil von
Arkhiv patologii, 2012-01, Vol.74 (1), p.12
Ort / Verlag
Russia (Federation)
Erscheinungsjahr
2012
Quelle
MEDLINE
Beschreibungen/Notizen
46 cases of nonendometrial carcinoma of the corpus uteri have been studied. The expressions of E-cadherin, alpha and beta-catenins were detected by immunohistochemical method. The high level of studied markers expression was founded out in clear cell carcinoma, whereas the less expression was detected in the corpus uteri of patients with serous, papillary, undifferentiated and mixed cancer. The absence of E-cadherin, alpha and beta-catenins complex expression correlated with unfavorable clinic-morphological features of carcinoma.