Details

Autor(en) / Beteiligte

• Bell, D S
• Barger, B O
• Go, R C
• Goldenberg, R L
• Perkins, L L
• Vanichanan, C J
• Roseman, J
• Acton, R T

Titel

Risk factors for gestational diabetes in black population

Ist Teil von

• Diabetes care, 1990-11, Vol.13 (11), p.1196

Ort / Verlag

United States

Erscheinungsjahr

1990

Quelle

MEDLINE

Beschreibungen/Notizen

• In a long-term longitudinal study of gestational diabetes mellitus in Black women, risk factors that were identified were age, obesity, a family history of diabetes, and the presence of hypertension. Poor predictors were a history of a previous large-for-date infant, parity, and age at first pregnancy. The prevalence of smooth muscle and nuclear autoantibodies was higher in gestational diabetic subjects. Gestational diabetic subjects who required insulin for glycemic control were more obese, had a lower frequency of the Bf-F phenotype and a higher frequency of the Bf-F1 phenotype, and had a lower frequency of the type 2 allele at the polymorphic locus adjacent to the insulin gene. Restriction-fragment-length polymorphisms flanking the insulin and apolipoprotein A-I and C-III genes, although not associated with gestational diabetes mellitus, may be associated with hyperlipidemia and subsequent atherosclerosis.