Details

Autor(en) / Beteiligte

• Hron, F
• Hejda, V
• Feyereisl, J
• Safár, P
• Sochová, H

Titel

Quiscent trophoblastic disease

Ist Teil von

• Ceská gynekologie, 2011-12, Vol.76 (6), p.443

Ort / Verlag

Czech Republic

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• Case report. Center for trophoblastic disease in Czech Republic, Institute for care of mother and child, 3rd Faculty of Medicine of Charles University Prague. The autors present a case of quiscent trophoblastic disease diagnosed at 27 years old primipara, secundigravida after previous molar pregnancy. The patient had low levels of serum hCG present for more than 18 months after the termination of pregnancy. After this period there was a malignant transformation associated with rapid elevation of hCG levels with need for chemotherapy which was succesfully completed. Quiscent (dormant, noninvasive) trophoblastic disease is a recently described unit defined by low levels of hCG present in patients serum and urine samples without any evidence of trophoblastic tumour or other source of hCG production. Quiscent trophoblastic disease is associated with high risk of malignant transformation.