Le infezioni in medicina, 2011-12, Vol.19 (4), p.224
2011
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Details
- Autor(en) / Beteiligte
- Titel
- NDM-1: the superbug?
- Ist Teil von
- Le infezioni in medicina, 2011-12, Vol.19 (4), p.224
- Ort / Verlag
- Italy
- Erscheinungsjahr
- 2011
- Quelle
- EZB-FREE-00999 freely available EZB journals
- Beschreibungen/Notizen
- A novel type of carbapenemase, New Delhi metallo beta-lactamase 1 (NDM 1), was first identified in 2008 in two Enterobacteriacea isolates, both recovered from a Swedish patient transferred from India. The emergence of NDM 1 is now reported from all continents, often in patients with a history of travel or hospitalization in the Indian subcontinent. The NDM 1 producing Gram-negative bacteria are mainly Enterobacteriaceae, which can cause colonization or fatal infections, with worrying antimicrobial susceptibility profiles: some isolates have developed resistance to practically all available antibiotics. Is the NDM-1 the super-bug? Are we in the post-antibiotic era? This review is a summary of currently available knowledge of NDM-1 that draws attention to future antimicrobial resistance scenarios.
- Sprache
- Italienisch
- Identifikatoren
- ISSN: 1124-9390Titel-ID: cdi_pubmed_primary_22212161
- Format
- –
- Schlagworte
- Abscess - drug therapy, Abscess - microbiology, Anti-Bacterial Agents - pharmacology, Anti-Bacterial Agents - therapeutic use, beta-Lactamases - drug effects, beta-Lactamases - metabolism, Buttocks, Colistin - pharmacology, Colistin - therapeutic use, Diabetes Complications, Drug Resistance, Multiple, Bacterial, Humans, India, Klebsiella Infections - complications, Klebsiella Infections - drug therapy, Klebsiella Infections - microbiology, Klebsiella pneumoniae - drug effects, Klebsiella pneumoniae - enzymology, Klebsiella pneumoniae - isolation & purification, Male, Microbial Sensitivity Tests, Middle Aged, Sweden, Travel, Treatment Outcome