Details

Autor(en) / Beteiligte

• Sigel, Astrid
• Sigel, Helmut
• Sigel, Roland Ko

Titel

Metal Ion-Promoted Conformational Changes of Oligonucleotides

Ist Teil von

• Interplay Between Metal Ions and Nucleic Acids, 2012, Vol.10, p.103-118

Ort / Verlag

The Netherlands: Springer Netherlands

Erscheinungsjahr

2012

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The review will discuss the influence of metal ions on conformational changes of oligonucleotides. First, a short definition of the torsion angles is given, followed by a concise yet critical overview of the commonly applied experimental techniques. Finally, the possible role of metals upon the following conformational changes of oligonucleotides is discussed: (i) the denaturation of double-strands, (ii) the transition from B- to A-DNA, (iii) the transition from right- to left-handed DNA and RNA, (iv) the condensation, (v) and other conformational changes. We conclude with a summary and outlook.