Details

Autor(en) / Beteiligte

• Camenzuli, Michelle
• Ritchie, Harald J
• Ladine, James R
• Shalliker, R. Andrew

Titel

The design of a new concept chromatography column

Ist Teil von

• Analyst (London), 2011-12, Vol.136 (24), p.5127-513

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2011

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Active Flow Management is a new separation technique whereby the flow of mobile phase and the injection of sample are introduced to the column in a manner that allows migration according to the principles of the infinite diameter column. A segmented flow outlet fitting allows for the separation of solvent or solute that elutes along the central radial section of the column from that of the sample or solvent that elutes along the wall region of the column. Separation efficiency on the analytical scale is increased by 25% with an increase in sensitivity by as much as 52% compared to conventional separations. Describes a new concept in the design of a HPLC column and introduces new analytical separation technology.